Overnight Safari from Cape Town
An overnight safari from Cape Town: the 2-day Garden Route Game Lodge trip with two game drives, the 2-day Karoo trip, and the reserves that sell a night, Aquila, Inverdoorn and Sanbona.
An overnight safari from Cape Town buys what a day cannot: a second game drive, at dawn, when the day trips are still on the road. Bokbus Garden Route Adventure Tours’ From Cape Town: 2-Day Safari at Garden Route Game Lodge, in the calendar below, drives the coast through Hermanus to Cape Agulhas, puts you on a sunset safari and a morning game drive at Garden Route Game Lodge, with dinner, a night in a 4-star chalet or lodge room and breakfast, and is from US$613 per person (checked November 2026). It has over 1,000 reviews and takes at most 12 guests.
The two days, as the trip runs them
| Day | In order |
|---|---|
| Day 1 | The coast road from Cape Town through Hermanus to Cape Agulhas, the southernmost tip of Africa, and its lighthouse; on to Garden Route Game Lodge for a sunset safari in an open vehicle; a three-course dinner; a night in a 4-star wooden chalet or lodge room |
| Day 2 | A morning game drive; breakfast and check-out; the drive back, reaching Cape Town in the evening |
Included: transport, fuel and tolls, a guide, the two game drives, the night, dinner and breakfast, and the stops at Hermanus, Betty’s Bay and Cape Agulhas. Not included: drinks, lunches and the Cape Agulhas lighthouse entry fee. The animals it lists for the drives are elephants, lions, rhinos, giraffes and hippos, among others, and it puts the lodge in a malaria-free region. Not suitable for people with mobility impairments or wheelchair users. Free cancellation up to 24 hours before.
It is on sale on selected days only. On 9 December 2026 it started at 6:00 AM: US$703.12 for one adult, or US$608.86 each for two adults. Pick your date in the calendar above.
Another two days: the Karoo route
Hotspots2c Tours' South African Wildlife and Safari 2-Day Tour is from US$345 per person (checked November 2026) and goes a different way: a shared 4x4 game drive of about two hours at Botlierskop Game Reserve, a night in Oudtshoorn in the accommodation package you choose, a bush drive at Buffelsdrift on day two, and Route 62 back. Its price swings with the date: US$367.66 per adult on 15 January 2027, US$861.19 each for two adults on 27 November 2026, a group tour that starts with two people. Breakfast is included; lunch, dinner and drinks are not. It is a lot of road, about 900 km in all and about six hours of driving each day, and it is plain about the leopard: unlikely on these drives. Not suitable for children under 8; free cancellation up to 2 days before.
Reserves that sell a night
If you would rather drive yourself and stay at the reserve:
- Aquila Private Game Reserve, about 175 km from Cape Town by its own figure: its overnight stays include full-board dining and both an afternoon and an early morning game drive (November 2026).
- Inverdoorn Game Reserve, about two and a half hours from Cape Town in the Tankwa Karoo: its pages describe stays of one, two or three nights.
- Sanbona Wildlife Reserve, about 3.5 hours by Route 62: 62,000 hectares in the Little Karoo outside Montagu, three lodges and twice-daily game drives, by its own pages.
All three call themselves malaria-free. Room rates are on each reserve’s own site.
A day or two?
From Cape Town: 2-Day Safari at Garden Route Game Lodge
Hermanus and Cape Agulhas on the way, a sunset and a morning game drive at Garden Route Game Lodge, dinner, breakfast and a night in a chalet or lodge room. At most 12 guests.
Check dates →From Cape Town: South African Wildlife and Safari 2-Day Tour
Hotspots2c Tours: Botlierskop and Buffelsdrift, a night in Oudtshoorn in the package you choose, and Route 62 back. Breakfast only; not for children under 8.
See the trip →From Cape Town: Safari Big 5 Game Reserve Sunset Game Drive
Mathew transport and tours' sunset safari: pickup in Cape Town at 11:00 AM, the reserve's entry fee and a 2-3 hour game drive. About 9 hours; no lunch on the list.
See the safari →Prices, ratings and review counts from the listings (GetYourGuide checked November 2026). Operators price by date, option and group size, so treat the figures as the shape of the market, not a quote.
Staying in Cape Town before or after? Where to stay in Cape Town has the pickup areas.
Two Days at Garden Route Game Lodge
Bokbus Garden Route Adventure Tours: Hermanus and Cape Agulhas, a sunset and a morning game drive, dinner, breakfast and a night in a chalet or lodge room.
Check dates